Physical dependence on the prescribed medication does not signify habit. Physical dependence requires the incidence of a withdrawal syndrome when There exists unexpected reduction or cessation in drug use or if an opiate antagonist is administered. Physical dependence is usually detected following a few days of opioid therapy. However, clinically c

Vigorous supportive therapy is required in severe intoxication. Treatments to limit the continuing absorption of the drug needs to be commonly executed Because the hepatic harm is dose dependent and occurs early in the course of intoxication.How rapidly an individual develops a tolerance may differ. Your body will begin to adapt on the medication i